|
|
O2 + arachidonic_acid <=> (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate
|
1.13.11.34
arachidonate 5-lipoxygenase
|
–
|
MK
|
|
BRENDA:
BR49525
KEGG:
R01595
MetaCyc:
ARACHIDONATE-5-LIPOXYGENASE-RXN
SABIO-RK:
1744
|
|
|
|
(6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate <=> leukotriene_A4 + H2O
|
1.13.11.34
arachidonate 5-lipoxygenase
|
–
|
MK
|
|
BRENDA:
BR49526
KEGG:
R03058
MetaCyc:
RXN-8647
|
|
|
|
2 glutathione + (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate <=> GSSG + 5-hydroxyeicosatetraenoic_acid + H2O
|
1.11.1.9
glutathione peroxidase
|
–
|
K
|
|
KEGG:
R07034
SABIO-RK:
7538
|
|
|
|
(6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate + reduced_acceptor <=> 5-hydroxyeicosatetraenoic_acid + H2O + acceptor
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-20570
|
|
|
|
arachidonic_acid + O2 <=> (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate + 7-HPETE + 9-HPETE
|
1.13.11.58
linoleate 9S-lipoxygenase
4.2.1.152
hydroperoxy icosatetraenoate dehydratase
|
–
–
|
|
|
BRENDA:
BS429899
|
|
|
|
(6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate <=> (7R)-hydroxy-(5S,6S)-epoxyeicosa-(8Z,11Z,14Z)-trienoic_acid + H2O
|
4.2.1.152
hydroperoxy icosatetraenoate dehydratase
5.4.4.7
hydroperoxy icosatetraenoate isomerase
|
–
–
|
|
|
BRENDA:
BS429097
|
|
|
|
(6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate + O2 <=> leukotriene_A4
|
1.13.11.34
arachidonate 5-lipoxygenase
|
–
|
|
|
BRENDA:
BS288902
|
|